Fredrik Åhs

Publications

Articles in journals
Articles, reviews/surveys
Conference papers

Articles in journals

Markant, A. , Tabrizi, F. , Grönvall, H. , Speed, D. & Åhs, F. (2025). Association Between Polygenic Risk Scores and Treatment Response to Antidepressants, Benzodiazepines, and Antihistamines in Anxiety and Depression. Biological Psychiatry Global Open Science, vol. 5: 3    

Balbuena, L. , Åhs, F. , Peters, E. , Mendes-Silva, A. & Speed, D. (2025). Does the Path From Cigarette Smoking to Suicide Death Go Through the Hospital? : A Causal Mediation Analysis in a National Canadian Sample. TOBACCO USE INSIGHTS, vol. 18    

Tabrizi, F. , Rosén, J. , Grönvall, H. , Rahimzadeh William-Olsson, V. , Arner, E. , Magnusson, P. K. , Palm, C. , Larsson, H. & et al. (2025). Heritability and polygenic load for comorbid anxiety and depression. Translational Psychiatry, vol. 15: 1    

Martensson, G. , Johansson, F. , Buhrman, M. , Åhs, F. & Clason van de Leur, J. (2024). A network analysis of exhaustion disorder symptoms throughout treatment. BMC Psychiatry, vol. 24: 1    

Bruin, W. B. , Zhutovsky, P. , van Wingen, G. A. , Bas-Hoogendam, J. M. , Groenewold, N. A. , Hilbert, K. , Winkler, A. M. , Zugman, A. & et al. (2024). Brain-based classification of youth with anxiety disorders : transdiagnostic examinations within the ENIGMA-Anxiety database using machine learning. Nature Mental Health, vol. 2: 1, pp. 104-118.  

Haim-Nachum, S. , Sopp, M. R. , Lüönd, A. M. , Afzal, N. , Åhs, F. , Allgaier, A. -. , Arévalo, A. , Asongwe, C. & et al. (2024). Childhood maltreatment is linked to larger preferred interpersonal distances towards friends and strangers across the globe. Translational Psychiatry, vol. 14: 1    

Hilbert, K. , Boeken, O. J. , Langhammer, T. , Groenewold, N. A. , Bas-Hoogendam, J. M. , Aghajani, M. , Zugman, A. , Åhs, F. & et al. (2024). Cortical and Subcortical Brain Alterations in Specific Phobia and Its Animal and Blood-Injection-Injury Subtypes : A Mega-Analysis From the ENIGMA Anxiety Working Group. American Journal of Psychiatry, vol. 181: 8, pp. 728-740.  

Wen, Z. , Pace-Schott, E. F. , Lazar, S. W. , Rosén, J. , Åhs, F. , Phelps, E. A. , LeDoux, J. E. & Milad, M. R. (2024). Distributed neural representations of conditioned threat in the human brain. Nature Communications, vol. 15: 1    

Sarling, A. , Sundin, Ö. , Åhs, F. , Gu, J. & Jansson, B. (2024). Factor structure and psychometric properties of a Swedish version of the Sussex-Oxford Compassion Scales (SOCS). Nordic Psychology, vol. 76: 1, pp. 78-96.  

Clason van de Leur, J. , Johansson, F. , McCracken, L. M. , Åhs, F. , Brodda Jansen, G. & Buhrman, M. (2024). Mediators during a Multimodal intervention for stress-induced exhaustion disorder. Cognitive Behaviour Therapy, vol. 53: 3, pp. 235-253.  

Gedin, F. , Blomé, S. , Kastrati, G. , Lalouni, M. , Åhs, F. , Fransson, P. , Rosén, J. , Thompson, W. H. & et al. (2024). Predicting long-term pain by combining brain imaging, genetics and health questionnaire data with Swedish national registries using a prospective superstruct design. Molecular Pain, vol. 20    

Fares-Otero, N. E. , Sharp, T. H. , Balle, S. R. , Quaatz, S. M. , Vieta, E. , Åhs, F. , Allgaier, A. -. , Arévalo, A. & et al. (2024). Social support and (complex) posttraumatic stress symptom severity : does gender matter?. European Journal of Psychotraumatology, vol. 15: 1    

Clason van de Leur, J. , Johansson, F. , McCracken, L. M. , Åhs, F. , Brodda Jansen, G. & Buhrman, M. (2023). Predictors and sub-groups in the treatment of stress-induced exhaustion disorder. Cognitive Behaviour Therapy, vol. 52: 4, pp. 397-418.  

Tabrizi, F. , Larsson, A. , Grönvall, H. , Söderstrand, L. , Hallén, E. , Champoux-Larsson, M. , Lundgren, T. , Sundström, F. & et al. (2023). Psychometric Evaluation of the Swedish Multidimensional Psychological Flexibility Inventory (MPFI). Cognitive Behaviour Therapy, vol. 52: 4, pp. 295-316.  

Rosén, J. , Kastrati, G. , Kuja-Halkola, R. , Larsson, H. & Åhs, F. (2022). A neuroimaging study of interpersonal distance in identical and fraternal twins.. Human Brain Mapping, vol. 43: 11, pp. 3508-3523.  

Frick, A. , Björkstrand, J. , Lubberink, M. , Eriksson, A. , Fredrikson, M. & Åhs, F. (2022). Dopamine and fear memory formation in the human amygdala. Molecular Psychiatry, vol. 27: 3, pp. 1704-1711.    

Kastrati, G. , Rosén, J. , Thompson, W. H. , Chen, X. , Larsson, H. , Nichols, T. E. , Tracey, I. , Fransson, P. & et al. (2022). Genetic Influence on Nociceptive Processing in the Human Brain-A Twin Study. Cerebral Cortex, vol. 32: 2, pp. 266-274.    

Kastrati, G. , Rosén, J. , Fredrikson, M. , Chen, X. , Kuja-Halkola, R. , Larsson, H. , Jensen, K. B. & Åhs, F. (2022). Genetic influences on central and peripheral nervous system activity during fear conditioning.. Translational Psychiatry, vol. 12: 1  

Tabrizi, F. , William-Olsson, V. R. , Rosén, J. , Grönvall, H. , Arner, E. , Magnusson, P. K. E. , Palm, C. , Larsson, H. & et al. (2022). P117. Predicting Genetic Risk for Depression and Anxiety Disorders. Biological Psychiatry, vol. 91  

Vinberg, K. , Rosén, J. , Kastrati, G. & Åhs, F. (2022). Whole brain correlates of individual differences in skin conductance responses during discriminative fear conditioning to social cues.. eLIFE, vol. 11    

Weis, J. , Persson, J. , Frick, A. , Åhs, F. , Versluis, M. & Alamidi, D. (2021). GABA quantification in human anterior cingulate cortex. PLOS ONE, vol. 16: 1  

Björkstrand, J. , Agren, T. , Frick, A. , Hjorth, O. , Furmark, T. , Fredrikson, M. & Åhs, F. (2020). Decrease in amygdala activity during repeated exposure to spider images predicts avoidance behavior in spider fearful individuals.. Translational Psychiatry, vol. 10: 1    

Björkstrand, J. , Karlsson, B. , Rosen, J. , Olsson, E. , Åhs, F. , Fredrikson, M. & Frick, A. (2020). High Unconditioned Stimulus Intensity Results in Stronger Threat Conditioning Than Low Intensity. Biological Psychiatry, vol. 87: 9, pp. S181-S181.

Costache, M. E. , Frick, A. , Månsson, K. , Engman, J. , Faria, V. , Hjorth, O. , Hoppe, J. M. , Gingnell, M. & et al. (2020). Higher- and lower-order personality traits and cluster subtypes in social anxiety disorder.. PLOS ONE, vol. 15: 4    

van de Leur, J. C. , Buhrman, M. , Åhs, F. , Rozental, A. & Jansen, G. B. (2020). Standardized multimodal intervention for stress-induced exhaustion disorder : an open trial in a clinical setting.. BMC Psychiatry, vol. 20: 1    

Rosén, J. , Kastrati, G. , Reppling, A. , Bergkvist, K. & Åhs, F. (2019). The effect of immersive virtual reality on proximal and conditioned threat. Scientific Reports, vol. 9: 1    

Hoppe, J. M. , Frick, A. , Åhs, F. , Linnman, C. , Appel, L. , Jonasson, M. , Lubberink, M. , Långström, B. & et al. (2018). Association between amygdala neurokinin-1 receptor availability and anxiety-related personality traits. Translational Psychiatry, vol. 8: 1    

Åhs, F. , Rosén, J. , Kastrati, G. , Fredrikson, M. , Agren, T. & Lundström, J. N. (2018). Biological preparedness and resistance to extinction of skin conductance responses conditioned to fear relevant animal pictures : A systematic review. Neuroscience and Biobehavioral Reviews, vol. 95, pp. 430-437.  

Mårtensson, J. , Lätt, J. , Åhs, F. , Fredrikson, M. , Söderlund, H. , Schiöth, H. B. , Kok, J. , Kremer, B. & et al. (2018). Diffusion tensor imaging and tractography of the white matter in normal aging : The rate-of-change differs between segments within tracts.. Magnetic Resonance Imaging, vol. 45, pp. 113-119.  

Frans, Ö. , Åhs, J. , Bihre, E. & Åhs, F. (2018). Distance to threat and risk of acute and posttraumatic stress disorder following bank robbery : A longitudinal study. Psychiatry Research, vol. 267, pp. 461-466.  

Rosén, J. , Kastrati, G. & Åhs, F. (2017). Social, proximal and conditioned threat. Neurobiology of Learning and Memory, vol. 142: Pt B, pp. 236-243.  

Björkstrand, J. , Agren, T. , Åhs, F. , Frick, A. , Larsson, E. , Hjorth, O. , Furmark, T. & Fredrikson, M. (2017). Think twice, it's all right : Long lasting effects of disrupted reconsolidation on brain and behavior in human long-term fear. Behavioural Brain Research, vol. 324, pp. 125-129.  

Åhs, F. , Gingnell, M. , Furmark, T. & Fredrikson, M. (2017). Within-session effect of repeated stress exposure on extinction circuitry function in social anxiety disorder. Psychiatry Research, vol. 261, pp. 85-90.    

Frick, A. , Åhs, F. , Palmquist, Å. M. , Pissiota, A. , Wallenquist, U. , Fernandez, M. , Jonasson, M. , Appel, L. & et al. (2016). Alterations in the serotonergic and substance P systems in posttraumatic stress disorder. Molecular Psychiatry, vol. 21: 10  

Björkstrand, J. , Agren, T. , Åhs, F. , Frick, A. , Larsson, E. , Hjorth, O. , Furmark, T. & Fredrikson, M. (2016). Disrupting Reconsolidation Attenuates Long-Term Fear Memory in the Human Amygdala and Facilitates Approach Behavior.. Current Biology, vol. 26: 19, pp. 2690-2695.  

Frick, A. , Åhs, F. , Palmquist, Å. M. , Pissiota, A. , Wallenquist, U. , Fernandez, M. , Jonasson, M. , Appel, L. & et al. (2016). Overlapping expression of serotonin transporters and neurokinin-1 receptors in posttraumatic stress disorder : a multi-tracer PET study. Molecular Psychiatry, vol. 21: 10, pp. 1400-7.  

Frick, A. , Åhs, F. , Appel, L. , Jonasson, M. , Wahlstedt, K. , Bani, M. , Merlo Pich, E. , Bettica, P. & et al. (2016). Reduced serotonin synthesis and regional cerebral blood flow after anxiolytic treatment of social anxiety disorder. European Neuropsychopharmacology, vol. 26: 11, pp. 1775-1783.  

Parma, V. , Ferraro, S. , Miller, S. S. , Åhs, F. & Lundström, J. N. (2015). Enhancement of Odor Sensitivity Following Repeated Odor and Visual Fear Conditioning. Chemical Senses, vol. 40: 7, pp. 497-506.    

Åhs, F. , Frick, A. , Furmark, T. & Fredrikson, M. (2015). Human serotonin transporter availability predicts fear conditioning. International Journal of Psychophysiology, vol. 98: 3 Pt 2, pp. 515-9.  

Frick, A. , Åhs, F. , Linnman, C. , Jonasson, M. , Appel, L. , Lubberink, M. , Långström, B. , Fredrikson, M. & et al. (2015). Increased neurokinin-1 receptor availability in the amygdala in social anxiety disorder : a positron emission tomography study with [11C]GR205171. Translational Psychiatry, vol. 5    

Åhs, F. , Kragel, P. A. , Zielinski, D. J. , Brady, R. & LaBar, K. S. (2015). Medial prefrontal pathways for the contextual regulation of extinguished fear in humans. NeuroImage, vol. 122, pp. 262-71.  

Frick, A. , Åhs, F. , Engman, J. , Jonasson, M. , Alaie, I. , Björkstrand, J. , Frans, Ö. , Faria, V. & et al. (2015). Serotonin Synthesis and Reuptake in Social Anxiety Disorder : A Positron Emission Tomography Study.. JAMA psychiatry, vol. 72: 8, pp. 794-802.  

Åhs, F. , Dunsmoor, J. E. , Zielinski, D. & LaBar, K. S. (2015). Spatial proximity amplifies valence in emotional memory and defensive approach-avoidance. Neuropsychologia, vol. 70, pp. 476-85.  

Juran, S. A. , Lundström, J. N. , Geigant, M. , Kumlien, E. , Fredrikson, M. , Åhs, F. & Olsson, M. J. (2015). Unilateral Resection of the Anterior Medial Temporal Lobe Impairs Odor Identification and Valence Perception. Frontiers in Psychology, vol. 6    

Faria, V. , Åhs, F. , Appel, L. , Linnman, C. , Bani, M. , Bettica, P. , Pich, E. M. , Fredrikson, M. & et al. (2014). Amygdala-frontal couplings characterizing SSRI and placebo response in social anxiety disorder. International Journal of Neuropsychopharmacology, vol. 17: 8, pp. 1149-57.    

Bergman, O. , Åhs, F. , Furmark, T. , Appel, L. , Linnman, C. , Faria, V. , Bani, M. , Pich, E. M. & et al. (2014). Association between amygdala reactivity and a dopamine transporter gene polymorphism. Translational Psychiatry, vol. 4  

Dunsmoor, J. E. , Åhs, F. , Zielinski, D. J. & LaBar, K. S. (2014). Extinction in multiple virtual reality contexts diminishes fear reinstatement in humans. Neurobiology of Learning and Memory, vol. 113, pp. 157-164.  

Åhs, F. , Davis, C. F. , Gorka, A. X. & Hariri, A. R. (2014). Feature-based representations of emotional facial expressions in the human amygdala.. Social Cognitive & Affective Neuroscience, vol. 9: 9, pp. 1372-1378.    

Åhs, F. , Engman, J. , Persson, J. , Larsson, E. , Wikström, J. , Kumlien, E. & Fredrikson, M. (2014). Medial temporal lobe resection attenuates superior temporal sulcus response to faces. Neuropsychologia, vol. 61, pp. 291-298.  

Åhs, F. , Miller, S. S. , Gordon, A. R. & Lundström, J. N. (2013). Aversive learning increases sensory detection sensitivity. Biological Psychology, vol. 92: 2, pp. 135-41.  

Zuurbier, L. A. , Nikolova, Y. S. , Åhs, F. & Hariri, A. R. (2013). Uncinate fasciculus fractional anisotropy correlates with typical use of reappraisal in women but not men. Emotion, vol. 13: 3, pp. 385-390.  

Hillert, L. , Jovanovic, H. , Åhs, F. & Savic, I. (2013). Women with multiple chemical sensitivity have increased harm avoidance and reduced 5-HT(1A) receptor binding potential in the anterior cingulate and amygdala. PLOS ONE, vol. 8: 1  

Thayer, J. F. , Åhs, F. , Fredrikson, M. , Sollers, J. J. & Wager, T. D. (2012). A meta-analysis of heart rate variability and neuroimaging studies : implications for heart rate variability as a marker of stress and health.. Neuroscience and Biobehavioral Reviews, vol. 36: 2, pp. 747-56.  

Engman, J. , Åhs, F. , Furmark, T. , Linnman, C. , Pissiota, A. , Appel, L. , Frans, Ö. , Långström, B. & et al. (2012). Age, sex and NK1 receptors in the human brain -- a positron emission tomography study with [¹¹C]GR205171. European Neuropsychopharmacology, vol. 22: 8, pp. 562-8.  

Faria, V. , Appel, L. , Åhs, F. , Linnman, C. , Pissiota, A. , Frans, Ö. , Bani, M. , Bettica, P. & et al. (2012). Amygdala subregions tied to SSRI and placebo response in patients with social anxiety disorder. Neuropsychopharmacology, vol. 37: 10, pp. 2222-32.  

Danfors, T. , Åhs, F. , Appel, L. , Linnman, C. , Fredrikson, M. , Furmark, T. & Kumlien, E. (2011). Increased neurokinin-1 receptor availability in temporal lobe epilepsy : a positron emission tomography study using [(11)C]GR205171. Epilepsy Research, vol. 97: 1-2, pp. 183-9.  

Dunsmoor, J. E. , Åhs, F. & Labar, K. S. (2011). Neurocognitive mechanisms of fear conditioning and vulnerability to anxiety. Frontiers in Human Neuroscience, vol. 5  

Laukka, P. , Åhs, F. , Furmark, T. & Fredrikson, M. (2011). Neurofunctional correlates of expressed vocal affect in social phobia. Cognitive, Affective, & Behavioral Neuroscience, vol. 11: 3, pp. 413-25.  

Åhs, F. , Kumlien, E. & Fredrikson, M. (2010). Arousal enhanced memory retention is eliminated following temporal lobe resection. Brain and Cognition, vol. 73: 3, pp. 176-179.  

Palmquist, A. M. , Pissiota, A. , Frans, O. , Åhs, F. , Långström, B. , Bergström, M. & Fredrikson, M. (2010). Comment on "Decreased Neurokinin-1 (Substance P) Receptor Binding in Patients with Panic Disorder : Positron Emission Tomographic Study With [(18)F]SPA-RQ". Biological Psychiatry, vol. 67: 4, pp. e25-e26.  

Åhs, F. , Frans, Ö. , Tibblin, B. , Kumlien, E. & Fredrikson, M. (2010). The effects of medial temporal lobe resections on verbal threat and fear conditioning. Biological Psychology, vol. 83: 1, pp. 41-46.  

Åhs, F. , Pissiota, A. , Michelgård, Å. , Frans, Ö. , Furmark, T. , Appel, L. & Fredrikson, M. (2009). Disentangling the web of fear : amygdala reactivity and functional connectivity in spider and snake phobia. Psychiatry Research, vol. 172: 2, pp. 103-108.  

Furmark, T. , Henningsson, S. , Appel, L. , Åhs, F. , Linnman, C. , Pissiota, A. , Faria, V. , Oreland, L. & et al. (2009). Genotype over-diagnosis in amygdala responsiveness : affective processing in social anxiety disorder. Journal of Psychiatry & Neuroscience, vol. 34: 1, pp. 30-40.

Ahs, F. , Sollers, J. J. , Furmark, T. , Fredrikson, M. & Thayer, J. F. (2009). High-frequency heart rate variability and cortico-striatal activity in men and women with social phobia. NeuroImage, vol. 47: 3, pp. 815-20.  

Furmark, T. , Appel, L. , Henningsson, S. , Åhs, F. , Faria, V. , Linnman, C. , Pissiota, A. , Frans, O. & et al. (2008). A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety. Journal of Neuroscience, vol. 28: 49, pp. 13066-74.  

Åhs, F. , Furmark, T. , Michelgård, Å. , Långström, B. , Appel, L. , Wolf, O. T. , Kirschbaum, C. & Fredrikson, M. (2006). Hypothalamic blood flow correlates positively with stress-induced cortisol levels in subjects with social anxiety disorder. Psychosomatic Medicine, vol. 68: 6, pp. 859-62.  

Furmark, T. , Appel, L. , Michelgård, Å. , Wahlstedt, K. , Åhs, F. , Zancan, S. , Jacobsson, E. , Flyckt, K. & et al. (2005). Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo. Biological Psychiatry, vol. 58: 2, pp. 132-142.  

Articles, reviews/surveys

Bas-Hoogendam, J. M. , Groenewold, N. A. , Aghajani, M. , Freitag, G. F. , Harrewijn, A. , Hilbert, K. , Jahanshad, N. , Thomopoulos, S. I. & et al. (2022). ENIGMA-anxiety working group : Rationale for and organization of large-scale neuroimaging studies of anxiety disorders. Human Brain Mapping, vol. 43: 1, pp. 83-112.    

Pfaltz, M. C. , Halligan, S. L. , Haim-Nachum, S. , Sopp, M. R. , Åhs, F. , Bachem, R. , Bartoli, E. , Belete, H. & et al. (2022). Social Functioning in Individuals Affected by Childhood Maltreatment : Establishing a Research Agenda to Inform Interventions. Psychotherapy and Psychosomatics, vol. 91: 4, pp. 238-251.    

Conference papers

Tabrizi, F. , Bernhardsson, J. , Rosén, J. , Grönvall, H. , Jansson, B. , Sundin, Ö. & Åhs, F. (2023). PHYSIOLOGICAL AND IMMUNOLOGICAL RESPONSES TO THE TRIER SOCIAL STRESS TEST. Paper presented at the Society for Psychophysiological Research - Annual Meeting 2023  

Åhs, F. , Mozelius, P. & Espvall, M. (2022). Preparing Psychologists and Social Workers for the Daily Use of AI. In Proceedings of European Conference on the Impact of AI and Robotics. (Proceedings of the European conference on the impact of artificial intelligence and robotics). pp. 1--5.  

Tabrizi, F. , Rahimzadeh William-Olsson, V. , Rosén, J. , Grönvall, H. , Arner, E. , Magnusson, P. K. , Palm, C. , Larsson, H. & et al. (2021). Prediction of anxiety and depression from polygenic scores in Swedish twins. In Abstracts of the WASAD Congress 2021 : an International Congress of the World Association for Stress Related and Anxiety Disorders, Vienna, Austria, September 20–22, 2021... pp. 1802--1803.  

Åhs, F. , Mozelius, P. & Dobslaw, F. (2020). Artificial Intelligence Supported Cognitive Behavioral Therapy for Treatment of Speech Anxiety in Virtual Reality Environments. In Proceedings of the European Conference on the Impact of Artificial Intelligence and Robotics. Reading, UK :    

Bjärtå, A. , Bernhardsson, J. , Tjernberg, M. , Åhs, F. & Sundin, Ö. (2019). Brief Intervention For Distress Related To Difficult And Traumatic Memories. In Libro de Actas. Granada : . pp. 268-